Quality control: from molecules to organelles

Quality control and organelle trafficking: ensuring functional organelles and cells

Mitochondrial quality control Jason Nielson (Rutter laboratory, University of Utah/Howard Hughes Medical Institute) described a protein quality control system centered on the Vms1-Cdc48 complex. This protein complex translocates to the mitochondrial outer membrane in response to various mitochondrial stresses, particularly those that elicit mitochondrial oxidant production. The search for the m...

From Software Quality Control to Quality Assurance

This paper addresses the transformation of traditional software quality control techniques to a proactive quality assurance program within embedded systems and other mission critical software: Software plays an increasingly important role in every product and organization. The number of mission critical applications, those with a high cost of failure (air traffic control systems and other life ...

Ancient invasions: from endosymbionts to organelles.

The acquisitions of mitochondria and plastids were important events in the evolution of the eukaryotic cell, supplying it with compartmentalized bioenergetic and biosynthetic factories. Ancient invasions by eubacteria through symbiosis more than a billion years ago initiated these processes. Advances in geochemistry, molecular phylogeny, and cell biology have offered insight into complex molecu...

From Molecules to Morphology

From Molecules to Organisms

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